Scientists used GAGE-seq (genome architecture and gene expression by sequencing), a technique that measures both gene expression and physical contacts in the same single cell.

This valuable study provides a cross-species single-cell transcriptomic resource for early female gonadal development in mammals. The data supporting the main conclusion remain incomplete, and ...

Over the last few years, the single-cell landscape has transitioned from mapping individual cellular transcriptomes to ...

How does a single cell build a brain with billions of precisely organized neurons? Researchers suggest that brain cells use their lineage—their cellular family tree—as a kind of positional map. Cells ...

Virtual cell models that enable the prediction of cell behavior across scales and biological contexts are rapidly emerging at the forefront of drug discovery. Tom Sercu, PhD, vice president of AI and ...

Scientists have long dreamed of discovering the alchemy by which chemicals can be turned into life. On Wednesday, a team at the University of Minnesota announced that it had taken a major step toward ...

Knights of science have long chased a biologic holy grail: transforming a soup of raw chemicals into self-sustaining life. Now, a team led by synthetic biologist Kate Adamala, of the University of ...